“Developing Prophylactics Against Stress-induced Depression”: Christine Ann Denny, Ph.D., Assistant Professor, Psychiatry, Columbia University and Research Scientist, NYS Psychiatric carries out laboratory research on the molecular mechanisms underlying learning and memory and stress. Stress exposure is a major risk factor for mood disorders, such as major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). Some individuals can successfully adapt to stress and do not develop mood disorders, an ability known as stress resilience. She will describe her work on developing prophylactics against stress-induced depressive-like behavior and in understanding how rapid-acting antidepressants, such as ketamine, are able to improve mood. Tuesday Talks are scheduled in Faculty House on the Morningside campus on alternate Tuesdays during the academic year. EPIC members, faculty, and invited guests speak on topics that range across the academic spectrum and also address issues of particular importance to the retired academic community. Participants can continue their discussion at lunch in the Faculty House Dining Room at a special reduced rate for EPIC members. Guests are welcome.